Current Pharmacological Treatment of Painful Diabetic Neuropathy: A Narrative Review
نویسندگان
چکیده
منابع مشابه
Treatment of painful diabetic neuropathy.
P neuropathy is one of the commonest long term complications of diabetes mellitus which has been reported to be prevalent in 22% of d iabe t i c cohor t . 1 Pa in fu l d iabe t i c neuropathy (PDN) occurs in 6% of the patients with diabetic peripheral neuropathy (DPN) and this is most distressing symptom which impairs quality of life.2 Patients seek advice to get relief but unfortunately treatm...
متن کاملPharmacological treatment of diabetic peripheral neuropathy.
Pain modulation is a key treatment goal for diabetic peripheral neuropathy patients. Guidelines have recommended antidepressant, anticonvulsant, analgesic, and topical medications-both approved and off-label-to reduce pain in this population.
متن کاملPainful Diabetic Neuropathy
N europathic pain exerts a substantial impact on quality of life, particularly by causing considerable interference in sleep, daily activities, and enjoyment of life. Chronic neuropathic pain is present in 13–26% of diabetic patients (1– 4). In a recent survey from Augsburg, Germany, the prevalence of painful polyneuropathy was found to be 13.3% in diabetic subjects, 8.7% in individuals with im...
متن کاملSurgical Management of Painful Diabetic Peripheral Neuropathy: A Focused Review
Peripheral diabeticneuropathy (PDN) is one of the major complications arising in patients with diabetes.A triad of metabolic abnormalities is known that render the peripheral nerve in diabetes mellitus susceptible to chronic compression: conversion of glucose to sorbitol increases the intraneural water content, slowing of axoplasmic transport of proteins hinders structural repair, glycosylation...
متن کاملPainful diabetic neuropathy.
PDN is commonly caused by involvement of either the C fibres or the Aδ fibres. PDN caused by the involvement of small nerve fibers (C fibres), may present without objective clinical findings, such as decreased peripheral reflexes or abnormalities, on routine electrophysiological studies. Small fiber neuropathies may manifest as a number of different clinical symptoms, including allodynia, burni...
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ژورنال
عنوان ژورنال: Medicina
سال: 2020
ISSN: 1648-9144
DOI: 10.3390/medicina56010025